Dear Antonia Cristina, First I want to apologize for the delayed response to your e-mail. That is because I was travelling abroad for business matters. Regarding your question I would like to say that colleagues in Copenhagen Fertility Centre advised you well. Seeking for egg donation is the proper choice at the point we are if we want good and direct results since you have already tried conventional ICSI with no results. It is true that in women age >42years the egg-DNA quality and egg quantity decreases compared with younger women. That means that you may experience ovulation and menstruation (thought some times you do not), but a pregnancy is unlikely to occur, or if it occurs, most often it is driven to early miscarriage (biochemical pregnancy), due to age, of egg/sperm, induced genetic impairment. Therefore egg-donation seems to be the proper solution. Our donation program is quite extended and well established, with more than 2000cycles/year. The whole procedure is by law strictly confidential and anonymous. All donors are of age <30 years with proven fertility and are being examined for haemoglonopathies, chromosomal defects (karyotype), blood/ rhesus type and infectious diseases (hepatides, HIV, RPR). We always try to match couples and donors in critical characteristics like blood/rhesus type, eyes, skin colour and special preferences. So, regarding your question the chances of getting pregnant are pretty good exceeding 50%/cycle. Other factors, like endometrial receptivity, smoking, alcohol consumption, autoimmune disease or thrombophilia can depress fertility and pregnancy rates, but all these are parameters that we successfully deal with. Sperm freezing can be done in Coppenhagen, but there must be some kind of communication between fertility centres directly as sperm is consider to be a biological specimen and there are specific rules in Europe, regarding transportation of biological specimens. We hope the best of luck to your trial, we expect to shortly hearing from you and thank you for your queries.